Estudos científicos

  1. Suhyeon Kim, Kyungae Jo, Ki-Bae Hong, Sung Hee Han & Hyung Joo Suh (2019) GABA and l-theanine mixture decreases sleep latency and improves NREM sleep, Pharmaceutical Biology, 57:1, 64-72, DOI: 1080/13880209.2018.1557698 [Link]
  2. Spinweber, C.L. L-Tryptophan administered to chronic sleep-onset insomniacs: Late-appearing reduction of sleep latency. Psychopharmacology90, 151–155 (1986). https://doi.org/10.1007/BF00181230  [Link]
  3. Huajun Xu, Chujun Zhang, Yingjun Qian, Jianyin Zou, Xinyi Li, Yupu Liu, Huaming Zhu, Lili Meng, Suru Liu, Weitian Zhang, Hongliang Yi, Jian Guan, Zhengnong Chen, Shankai Yin, Efficacy of melatonin for sleep disturbance in middle-aged primary insomnia: a double-blind, randomised clinical trial,Sleep Medicine, Volume 76, 2020, Pages 113-119, ISSN 1389-9457; [Link]
  4. Regulatory aspects and evidences of melatonin use for sleep disorders and insomnia: an integrative review; [Link]
  5. https://oswaldocruz.br/revista_academica /content/pdf/Edicao_23_RYCHARD _CAVALLI_ROSA[Link]
  6. Syed EU, Wasay M, Awan S. Vitamin B12 supplementation in treating major depressive disorder: a randomized controlled trial. Open Neurol J. 2013 Nov 15;7:44-8. doi: 10.2174/1874205X01307010044. PMID: 24339839; PMCID: PMC3856388. [Link]
  7. Lee J, Jung HY, Lee SI, Choi JH, Kim SG. Effects of Passiflora incarnata Linnaeus on polysomnographic sleep parameters in subjects with insomnia disorder: a double-blind randomized placebo-controlled study. Int Clin Psychopharmacol. 2020 Jan;35(1):29-35. doi: 10.1097/YIC.0000000000000291. PMID: 31714321. [Link]
  8. Krause AJ, Simon EB, Mander BA, Greer SM, Saletin JM, Goldstein-Piekarski AN, Walker MP. The sleep-deprived human brain. Nat Rev Neurosci. 2017 Jul;18(7):404-418. doi: 10.1038/nrn.2017.55. Epub 2017 May 18. PMID: 28515433; PMCID: PMC6143346. [Link]
  9. Chaput JP, McHill AW, Cox RC, Broussard JL, Dutil C, da Costa BGG, Sampasa-Kanyinga H, Wright KP Jr. The role of insufficient sleep and circadian misalignment in obesity. Nat Rev Endocrinol. 2023 Feb;19(2):82-97. doi: 10.1038/s41574-022-00747-7. Epub 2022 Oct 24. PMID: 36280789; PMCID: PMC9590398. [Link]
  10. Lewis LD. The interconnected causes and consequences of sleep in the brain. Science. 2021 Oct 29;374(6567):564-568. doi: [Link] 10.1126/science.abi8375. Epub 2021 Oct 28. PMID: 34709917; PMCID: PMC8815779. [Link]